Zest 2.0 is now shipping •Get Up To 35% off on Subscribe & Save •Free shipping and easy cancellations •30-day money back guarantee •

Zest 2.0 is now shipping •Get Up To 35% off on Subscribe & Save •Free shipping and easy cancellations •30-day money back guarantee •

Zest 2.0 is now shipping •Get Up To 35% off on Subscribe & Save •Free shipping and easy cancellations •30-day money back guarantee •

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TIMED-RELEASE CAFFEINE

Wake Up Pill

4.7 • 141 reviews
Developed by sleep experts and validated in , our wake-up supplement supports waking up refreshed, and helps counteract sleep inertia.
$59.95
30% OFF
35% OFF
30-DAY MONEY-BACK GUARANTEE
FREE SHIPPING FOR SUBSCRIPTIONS
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Limited inventory! Order soon.

Due to high demand, limited inventory is available.
2342+ ordered recently.

82% RESERVED 18% AVAILABLE
  1. Counteracts sleep inertia and morning grogginess†
  2. Supports cognitive performance and mood upon waking up
  3. Supports healthy circadian rhythm alignment

Science-based, all natural formulation:

Caffeine
L-Theanine
Zinc
Vitamin B5
Vitamin B6
Vitamin B12

Rigorous quality standards:

Vegan
Non-GMO
Gluten free
No Sugar
Lactose free

Ingredients per capsule: Caffeine, L-Theanine, Vitamin B5 (as Calcium D-Pantothenate), Vitamin B6 (as Pyridoxine Hydrochloride), Vitamin B12 (as Methylcobalamin), Zinc Bisglycinat, Microcrystalline Cellulose Pellets, Hydroxypropyl Methylcellulose, Anionic Methacrylate Copolymer, Mono- and Diglycerides of Fatty Acids, Calcium Carbonate, Triethyl Citrate, Isomalt, Iron Oxide Red, Polysorbate 80, Medium Chain Tryglycerides

Take two (2) capsules whole with half a glass of water before going to bed.

Do not chew or crush the capsule.

Zest Wake-Up Pill

Morning Wakefulness

Zest is formulated to help you wake up alert, energized, and mentally clear — without needing to reach for coffee.

Clinical Trial Results

  • In a double-blind, placebo-controlled study, participants who took the delayed-release caffeine before bed showed a 400% increase in physical readiness to move
  • 71% increase in mental clarity
  • 80% improvement in ease of waking — within 15 minutes of opening their eyes
  • These results reflect rapid, measurable improvements across all domains of sleep inertia: physical, cognitive, behavioral, and emotional

Cognitive Performance

Zest supports faster thinking and better decision-making during the most cognitively vulnerable part of your day: right after waking.

Clinical Trial Results

  • Participants had significantly faster reaction times on the psychomotor vigilance test (PVT)
  • Showed improved neurobehavioral performance vs placebo — even after just 4 hours of sleep
  • This marks the first time a proactive, time-synced caffeine product has shown improvements in objective cognitive metrics immediately post-wake

Mood & Emotional Well-Being

Zest promotes a positive emotional state upon waking, helping you start your day with motivation and mental resilience.

Clinical Trial Results

  • On the PANAS (Positive and Negative Affect Scale), participants reported a significant boost in positive affect
  • A trend toward reduced negative mood within 15 minutes of waking
  • The caffeine formulation's effects were linked to dopamine activation in mood-related brain regions like the nucleus accumbens

Circadian Alignment

Zest is designed to complement your natural biological rhythms — amplifying your body’s natural cortisol spike in the morning without interfering with sleep onset.

Clinical Trial Results

  • Salivary cortisol measurements showed a significant increase in cortisol levels at 60 minutes post-awakening in the caffeine group vs placebo
  • Aligning with the natural cortisol awakening response (CAR)
  • This suggests Zest supports healthy HPA-axis function and wake-up hormone dynamics

Sleep Integrity

Zest is engineered for nighttime use — designed to activate about 8 hours later, without disrupting your ability to fall asleep.

Additionally, since the study, we've improved the formulation and capsule technology to prevent disruption of sleep from food-induced digestive activity.

Clinical Trial Results

  • Despite being taken at bedtime, the formulation showed no significant impact on sleep latency, REM sleep, or sleep efficiency in a restricted 4-hour sleep window
  • The only change was a minor (~17-minute) reduction in deep sleep (N3) under specific conditions where a meal was given mid-night.
  • This suggests that under normal fasting conditions, Zest preserves sleep quality

Dornbierer, D.A., Yerlikaya, F., Wespi, R. et al. A novel bedtime pulsatile-release caffeine formula ameliorates sleep inertia symptoms immediately upon awakening. Sci Rep 11, 19734 (2021). View Full Study

Dr. Sohaib Imtiaz

Dr. Sohaib Imtiaz, MD

Zest Medical Advisor

“So many people struggle with mornings — fatigue, fog, snoozing for an hour. Zest’s delayed-release caffeine solves that in a way that aligns with how your biology actually works. As a longevity doctor, it’s one of the few sleep and energy products I genuinely recommend.”

Zest Wake-Up Pill

Morning Wakefulness

Zest is formulated to help you wake up alert, energized, and mentally clear — without needing to reach for coffee.

Clinical Trial Results

  • In a double-blind, placebo-controlled study, participants who took the delayed-release caffeine before bed showed a 400% increase in physical readiness to move
  • 71% increase in mental clarity
  • 80% improvement in ease of waking — within 15 minutes of opening their eyes
  • These results reflect rapid, measurable improvements across all domains of sleep inertia: physical, cognitive, behavioral, and emotional

Cognitive Performance

Zest supports faster thinking and better decision-making during the most cognitively vulnerable part of your day: right after waking.

Clinical Trial Results

  • Participants had significantly faster reaction times on the psychomotor vigilance test (PVT)
  • Showed improved neurobehavioral performance vs placebo — even after just 4 hours of sleep
  • This marks the first time a proactive, time-synced caffeine product has shown improvements in objective cognitive metrics immediately post-wake

Mood & Emotional Well-Being

Zest promotes a positive emotional state upon waking, helping you start your day with motivation and mental resilience.

Clinical Trial Results

  • On the PANAS (Positive and Negative Affect Scale), participants reported a significant boost in positive affect
  • A trend toward reduced negative mood within 15 minutes of waking
  • The caffeine formulation's effects were linked to dopamine activation in mood-related brain regions like the nucleus accumbens

Circadian Alignment

Zest is designed to complement your natural biological rhythms — amplifying your body’s natural cortisol spike in the morning without interfering with sleep onset.

Clinical Trial Results

  • Salivary cortisol measurements showed a significant increase in cortisol levels at 60 minutes post-awakening in the caffeine group vs placebo
  • Aligning with the natural cortisol awakening response (CAR)
  • This suggests Zest supports healthy HPA-axis function and wake-up hormone dynamics

Sleep Integrity

Zest is engineered for nighttime use — designed to activate about 8 hours later, without disrupting your ability to fall asleep.

Additionally, since the study, we've improved the formulation and capsule technology to prevent disruption of sleep from food-induced digestive activity.

Clinical Trial Results

  • Despite being taken at bedtime, the formulation showed no significant impact on sleep latency, REM sleep, or sleep efficiency in a restricted 4-hour sleep window
  • The only change was a minor (~17-minute) reduction in deep sleep (N3) under specific conditions where a meal was given mid-night.
  • This suggests that under normal fasting conditions, Zest preserves sleep quality

Dornbierer, D.A., Yerlikaya, F., Wespi, R. et al. A novel bedtime pulsatile-release caffeine formula ameliorates sleep inertia symptoms immediately upon awakening. Sci Rep 11, 19734 (2021). View Full Study

More Zest. More Energy. Less Grogginess. Better Mood. Innovative Science. Expert Formulation. All-Natural Ingredients. Proprietary Capsule Technology.
More Zest. More Energy. Less Grogginess. Better Mood. Innovative Science. Expert Formulation. All-Natural Ingredients. Proprietary Capsule Technology.
More Zest. More Energy. Less Grogginess. Better Mood. Innovative Science. Expert Formulation. All-Natural Ingredients. Proprietary Capsule Technology.
More Zest. More Energy. Less Grogginess. Better Mood. Innovative Science. Expert Formulation. All-Natural Ingredients. Proprietary Capsule Technology.
More Zest. More Energy. Less Grogginess. Better Mood. Innovative Science. Expert Formulation. All-Natural Ingredients. Proprietary Capsule Technology.
More Zest. More Energy. Less Grogginess. Better Mood. Innovative Science. Expert Formulation. All-Natural Ingredients. Proprietary Capsule Technology.
More Zest. More Energy. Less Grogginess. Better Mood. Innovative Science. Expert Formulation. All-Natural Ingredients. Proprietary Capsule Technology.
More Zest. More Energy. Less Grogginess. Better Mood. Innovative Science. Expert Formulation. All-Natural Ingredients. Proprietary Capsule Technology.

Say hello to better mornings

Meet the world's
first wake-up pill.

Designed to be taken before bed, our patented delayed-release technology releases our formula 7-8 hours later to jumpstart your mornings.

Pill

Formulation

Caffeine
80mg

Boosts metabolism and energy levels, enhances alertness, focus, and performance

L-Theanine
80mg

Supports relaxed alertness, mental clarity, and smooth, sustained focus

Vitamin B5
6.7mg

Supports mental performance, nervous system function and reduces fatigue

Vitamin B6
1.4mg

Supports cognitive function, neurotransmitter function, and reduces fatigue

View All Ingredients

Vitamin B12
80mcg

Supports cellular energy production, nervous system function, energy metabolism, and cognition.

Zinc
3.3mg

Supports healthy cognition

Welcome aboard

Wake up, and take off.
Take ZestSleepWake upLiveEnergy level
10:00PM

Take Zest before bed, best on empty stomach

03:00AM

During sleep the coating dissolves after a delay

06:00AM

The core is released shortly before waking up

10:00AM

Sustained energy throughout your day

Timeline

Better mornings, better energy for life.
Absorption process visualization
Icon
Hour 08

Begin your journey

Experience a gradual, well-timed release of caffeine designed to align with your natural wake-up rhythm.

Consistent use helps support steadier mornings
Icon
Day 03

Steady mornings

Consistent use helps support steadier mornings. You may notice less grogginess and improved focus.

Energy improvement visualization
Icon
Day 30

Better energy management

Regular use contributes to better energy management, supporting your body's ability to maintain consistent sleep-wake patterns.

Peak performance visualization
Icon
Day 60+

Natural rhythm alignment

Many longterm users report feeling more refreshed and aligned with their natural circadian rhythms, enhancing overall productivity and focus.

†Based on available scientific data from scientific studies and customer reviews.

Built different

Instant morning energy, without the afternoon crash.

Sleep SupplementsCoffee & TeaEnergy DrinksOther Caffeine-Based Products
Taken Before Bed
Counteracts Morning Grogginess Instantly
Proprietary Timed-Release Formula
Prevents Afternoon Crash
0 Calories / Sugar
†Based on current available data for mass market products & brands.
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Science is in our core

Formulated for better days.
Validated by research.

We've partnered with leading Swiss sleep and pharmaceutical scientists to engineer a first-of-its-kind, clinically validated formula.

10+

Years of research

In collaboration with University of Zurich and other leading research institutions, published in Nature Scientific Reports, and more

2

Human clinical trials

Completed human clinical trials demonstrating robustness of release profile and improvements in sleep inertia

4+

Ongoing field studies

We are continuing to conduct studies to further demonstrate the benefits of our formulations

2

Patents

Proprietary capsule and delivery technologies are protected under 2 patents

"It's like drinking coffee while you sleep"
- Brandon S
"I haven't woken up this good in like a decade. Wild."
- Justin Z
"Zest is f**king awesome. Hit me full-force like 30 minutes after waking up."
- Nico F
"Zest crushed it this morning."
- Isaiah G
"It's like drinking coffee while you sleep"
- Brandon S
"I haven't woken up this good in like a decade. Wild."
- Justin Z
"Zest is f**king awesome. Hit me full-force like 30 minutes after waking up."
- Nico F
"Zest crushed it this morning."
- Isaiah G
"It's like drinking coffee while you sleep"
- Brandon S
"I haven't woken up this good in like a decade. Wild."
- Justin Z
"Zest is f**king awesome. Hit me full-force like 30 minutes after waking up."
- Nico F
"Zest crushed it this morning."
- Isaiah G
"It's like drinking coffee while you sleep"
- Brandon S
"I haven't woken up this good in like a decade. Wild."
- Justin Z
"Zest is f**king awesome. Hit me full-force like 30 minutes after waking up."
- Nico F
"Zest crushed it this morning."
- Isaiah G
"It's like drinking coffee while you sleep"
- Brandon S
"I haven't woken up this good in like a decade. Wild."
- Justin Z
"Zest is f**king awesome. Hit me full-force like 30 minutes after waking up."
- Nico F
"Zest crushed it this morning."
- Isaiah G
"It's like drinking coffee while you sleep"
- Brandon S
"I haven't woken up this good in like a decade. Wild."
- Justin Z
"Zest is f**king awesome. Hit me full-force like 30 minutes after waking up."
- Nico F
"Zest crushed it this morning."
- Isaiah G
"It's like drinking coffee while you sleep"
- Brandon S
"I haven't woken up this good in like a decade. Wild."
- Justin Z
"Zest is f**king awesome. Hit me full-force like 30 minutes after waking up."
- Nico F
"Zest crushed it this morning."
- Isaiah G
"It's like drinking coffee while you sleep"
- Brandon S
"I haven't woken up this good in like a decade. Wild."
- Justin Z
"Zest is f**king awesome. Hit me full-force like 30 minutes after waking up."
- Nico F
"Zest crushed it this morning."
- Isaiah G

Got questions?
Our team of sleep experts have answers.

Does this replace my morning coffee?
Zest is formulated to contain about the same amount of caffeine as a cup of coffee. We are coffee lovers ourselves, and designed it so that it can be both a supplement or a replacement to coffee. If you find yourself wanting a cup of coffee in the morning or afternoon, you can do so without any issues.
What are the advantages of using Zest's delayed-release caffeine capsule over taking a regular caffeine pill in the morning?
When you consume caffeine, the caffeine embarks on a 15 to 20-minute journey through your small intestine, into your bloodstream. This typically means it make take half an hour or more, to feel the effects of a caffeine pill, or a cup of coffee - which is more time you'll have to spend suffering through symptoms of "sleep inertia" - the morning grogginess you typically feel in the morning when you first wake up. Zest's proprietary delayed-release capsule gradually releases caffeine and other active ingredients, after an initial 7 hour delay. This allows you to wake up with caffeine already in your bloodstream, counteracting sleep inertia and helping you feel alert and energized from the moment you wake up.
Why is caffeine more effective while asleep?
While you're awake and going about your day, a chemical compound called adenosine gradually accumulates in parts of your brain. Adenosine is typically what makes you feel drowsy and ready for bed. Caffeine works by binding to adenosine receptors in our brain. When caffeine binds to those receptors, it blocks our ability to feel the effects of adenosine, so we feel less sleepy, more energetic and focused. Because adenosine is cleared from your brain when you sleep, this frees up the receptors such that caffeine is able to more effectively bind to them. This effectively means that you'll be able to better feel the effects of caffeine, and feel more alert and focused as a result.
Does using a timed-release caffeine capsule restrict the amount of time I can sleep?
For the average person, the recommended amount of sleep time is around 7-9 hours. We've carefully designed our pill to best suit everyone's sleep needs, such that you'll only wake up after 7-8 hours. We recommend consistently taking the capsule for a few weeks, which will help your body naturally regulate a consistent sleep schedule and wake-up time.
How does caffeine affect my sleep cycles?
Typically, when you wake up during the later part of a sleep cycle, you may experience grogginess, as you are in REM sleep, or deep sleep, also known as NREM stage 3 and stage 4. This is often why short 20 minute naps are recommended over longer naps, unless you can sleep for a full 90-minute sleep cycle. We've designed our capsule to release caffeine towards the end of your sleep cycle, and timed it such that you're less likely to be in these stages when the caffeine activates. Additionally, once released, caffeine helps ensure that you wake up naturally from a lighter sleep stage and thus, mitigating the effects of sleep inertia from waking up suddenly from a deeper sleep stage.
What if I want to sleep for more than 8 hours?
If you need more than 8 hours of sleep, you can always opt to not take the timed-release capsule. Additionally, if your body is sleep-deprived, your accumulated sleep debt, and your corresponding "sleep drive" or "sleep pressure" may outweigh the caffeine's effects. This means you may not wake up from the caffeine.
How is Zest different from other timed-release caffeine products?
Our product stands out in several key ways: 1. Advanced Release Mechanism: Our delayed-release coating is highly advanced, developed in collaboration with pharmaceutical scientists and neuroscientists. Unlike other products, which may release caffeine prematurely, our formulation is designed to reliably release caffeine after 7–8 hours of sleep, ensuring you wake up feeling refreshed and alert. This has been clinically validated — read our published peer-reviewed study here. 2. True Delayed-Release, Not Just Extended/Sustained-Release: Many products labeled as "extended-release" or "sustained-release" gradually release caffeine over time, starting shortly after ingestion. In contrast, Zest is a true delayed-release system that holds off releasing caffeine for a full 7 hours, perfectly timed to coincide with waking up, sustained over the course of 2+ hours. This ensures the caffeine works exactly when you need it, without interfering with your sleep, and without causing a crash. 3. Scientifically Backed and Validated: We've invested heavily in the development and testing of our release technology to ensure robustness and reliability. Our formula has been rigorously tested to provide consistent results, so you don't wake up too early or experience uneven effects. 4. Premium Ingredients: We source the highest quality ingredients from trusted European suppliers in countries like Switzerland and Germany. This ensures both effectiveness and safety for our users. While our product is priced higher than some alternatives, we believe it delivers unparalleled quality and performance. If you're looking for a reliable, science-backed solution, we believe Zest to be the best option available. Learn more about our science and our background here.
What if I have insomnia?
This product is not intended to treat, cure, or prevent clinical sleep disorders. The following section is for educational and information purposes only, does not constitute providing medical advice. Always consult your physician or clinician before using this product. The gold standard treatment for insomnia is CBT-i. The first line of treatment technique in CBT-i is often "sleep restriction therapy", which involves restricting the amount of time you spend in bed. Zest can help support waking up at a set time every day, and help you better anchor your wake-up times to be more consistent. In this particular case, taking a caffeine-based product such as Zest can be beneficial for managing symptoms of insomnia and aligning your circadian rhythms.
I've heard I'm not supposed to consume caffeine until 90 minutes after waking up?
Don't worry - this recently trending advice from Dr. Huberman is not strongly supported by science. One of the biggest claims behind delaying caffeine is that it prevents interfering with the body's natural cortisol rhythm. But this argument is misleading. The idea that delaying caffeine prevents "extending" the cortisol peak is also flawed. Caffeine will still cause a rise in cortisol even if you delay intake, meaning the timing doesn't make much difference compared to the amount. If avoiding cortisol spikes were truly a concern, then morning workouts should also be discouraged—yet research overwhelmingly supports early exercise for energy and metabolism. To mitigate an afternoon crash, our timed-release capsule gradually releases caffeine, and maintains a more gradual and consistent level of caffeine in your bloodstream, avoiding any large spikes and subsequent crashes. This steady release helps sustain your energy levels throughout the day and avoid any afternoon crashes from caffeine. Read more here.