TIMED-RELEASE CAFFEINE
Wake Up Pill
Limited inventory! Order soon.
Due to high demand, limited inventory is available.
2368+ ordered in the last month.
- Counteracts sleep inertia and morning grogginess†
- Supports cognitive performance and mood upon waking up
- Supports healthy circadian rhythm alignment
Rigorous quality standards:
Ingredients per capsule: Caffeine, L-Theanine, Vitamin B5 (as Calcium D-Pantothenate), Vitamin B6 (as Pyridoxine Hydrochloride), Vitamin B12 (as Methylcobalamin), Zinc Bisglycinat, Microcrystalline Cellulose Pellets, Hydroxypropyl Methylcellulose, Anionic Methacrylate Copolymer, Mono- and Diglycerides of Fatty Acids, Calcium Carbonate, Triethyl Citrate, Isomalt, Iron Oxide Red, Polysorbate 80, Medium Chain Tryglycerides
Take two (2) capsules whole with half a glass of water before going to bed.
Do not chew or crush the capsule.
Zest Wake-Up Pill
Morning Wakefulness
Zest is formulated to help you wake up alert, energized, and mentally clear — without needing to reach for coffee.
Clinical Trial Results
- In a double-blind, placebo-controlled study, participants who took the delayed-release caffeine before bed showed a 400% increase in physical readiness to move
- 71% increase in mental clarity
- 80% improvement in ease of waking — within 15 minutes of opening their eyes
- These results reflect rapid, measurable improvements across all domains of sleep inertia: physical, cognitive, behavioral, and emotional
Cognitive Performance
Zest supports faster thinking and better decision-making during the most cognitively vulnerable part of your day: right after waking.
Clinical Trial Results
- Participants had significantly faster reaction times on the psychomotor vigilance test (PVT)
- Showed improved neurobehavioral performance vs placebo — even after just 4 hours of sleep
- This marks the first time a proactive, time-synced caffeine product has shown improvements in objective cognitive metrics immediately post-wake
Mood & Emotional Well-Being
Zest promotes a positive emotional state upon waking, helping you start your day with motivation and mental resilience.
Clinical Trial Results
- On the PANAS (Positive and Negative Affect Scale), participants reported a significant boost in positive affect
- A trend toward reduced negative mood within 15 minutes of waking
- The caffeine formulation's effects were linked to dopamine activation in mood-related brain regions like the nucleus accumbens
Circadian Alignment
Zest is designed to complement your natural biological rhythms — amplifying your body’s natural cortisol spike in the morning without interfering with sleep onset.
Clinical Trial Results
- Salivary cortisol measurements showed a significant increase in cortisol levels at 60 minutes post-awakening in the caffeine group vs placebo
- Aligning with the natural cortisol awakening response (CAR)
- This suggests Zest supports healthy HPA-axis function and wake-up hormone dynamics
Sleep Integrity
Zest is engineered for nighttime use — designed to activate about 8 hours later, without disrupting your ability to fall asleep.
Additionally, since the study, we've improved the formulation and capsule technology to prevent disruption of sleep from food-induced digestive activity.
Clinical Trial Results
- Despite being taken at bedtime, the formulation showed no significant impact on sleep latency, REM sleep, or sleep efficiency in a restricted 4-hour sleep window
- The only change was a minor (~17-minute) reduction in deep sleep (N3) under specific conditions where a meal was given mid-night.
- This suggests that under normal fasting conditions, Zest preserves sleep quality
Dornbierer, D.A., Yerlikaya, F., Wespi, R. et al. A novel bedtime pulsatile-release caffeine formula ameliorates sleep inertia symptoms immediately upon awakening. Sci Rep 11, 19734 (2021). View Full Study
Dr. Sohaib Imtiaz, MD
“So many people struggle with mornings — fatigue, fog, snoozing for an hour. Zest’s delayed-release caffeine solves that in a way that aligns with how your biology actually works. As a longevity doctor, it’s one of the few sleep and energy products I genuinely recommend.”
Zest Wake-Up Pill
Morning Wakefulness
Zest is formulated to help you wake up alert, energized, and mentally clear — without needing to reach for coffee.
Clinical Trial Results
- In a double-blind, placebo-controlled study, participants who took the delayed-release caffeine before bed showed a 400% increase in physical readiness to move
- 71% increase in mental clarity
- 80% improvement in ease of waking — within 15 minutes of opening their eyes
- These results reflect rapid, measurable improvements across all domains of sleep inertia: physical, cognitive, behavioral, and emotional
Cognitive Performance
Zest supports faster thinking and better decision-making during the most cognitively vulnerable part of your day: right after waking.
Clinical Trial Results
- Participants had significantly faster reaction times on the psychomotor vigilance test (PVT)
- Showed improved neurobehavioral performance vs placebo — even after just 4 hours of sleep
- This marks the first time a proactive, time-synced caffeine product has shown improvements in objective cognitive metrics immediately post-wake
Mood & Emotional Well-Being
Zest promotes a positive emotional state upon waking, helping you start your day with motivation and mental resilience.
Clinical Trial Results
- On the PANAS (Positive and Negative Affect Scale), participants reported a significant boost in positive affect
- A trend toward reduced negative mood within 15 minutes of waking
- The caffeine formulation's effects were linked to dopamine activation in mood-related brain regions like the nucleus accumbens
Circadian Alignment
Zest is designed to complement your natural biological rhythms — amplifying your body’s natural cortisol spike in the morning without interfering with sleep onset.
Clinical Trial Results
- Salivary cortisol measurements showed a significant increase in cortisol levels at 60 minutes post-awakening in the caffeine group vs placebo
- Aligning with the natural cortisol awakening response (CAR)
- This suggests Zest supports healthy HPA-axis function and wake-up hormone dynamics
Sleep Integrity
Zest is engineered for nighttime use — designed to activate about 8 hours later, without disrupting your ability to fall asleep.
Additionally, since the study, we've improved the formulation and capsule technology to prevent disruption of sleep from food-induced digestive activity.
Clinical Trial Results
- Despite being taken at bedtime, the formulation showed no significant impact on sleep latency, REM sleep, or sleep efficiency in a restricted 4-hour sleep window
- The only change was a minor (~17-minute) reduction in deep sleep (N3) under specific conditions where a meal was given mid-night.
- This suggests that under normal fasting conditions, Zest preserves sleep quality
Dornbierer, D.A., Yerlikaya, F., Wespi, R. et al. A novel bedtime pulsatile-release caffeine formula ameliorates sleep inertia symptoms immediately upon awakening. Sci Rep 11, 19734 (2021). View Full Study
Say hello to better mornings
Meet the world's
first wake-up pill.
Formulation
Welcome aboard
Take Zest before bed, best on empty stomach
During sleep the coating dissolves after a delay
The core is released shortly before waking up
Sustained energy throughout your day
Timeline
Begin your journey
Experience a gradual, well-timed release of caffeine designed to align with your natural wake-up rhythm.
Steady mornings
Consistent use helps support steadier mornings. You may notice less grogginess and improved focus.
Better energy management
Regular use contributes to better energy management, supporting your body's ability to maintain consistent sleep-wake patterns.
Natural rhythm alignment
Many longterm users report feeling more refreshed and aligned with their natural circadian rhythms, enhancing overall productivity and focus.
†Based on available scientific data from scientific studies and customer reviews.
Built different
Instant morning energy, without the afternoon crash.
| Sleep Supplements | Coffee & Tea | Energy Drinks | Other Caffeine-Based Products | ||
|---|---|---|---|---|---|
| Taken Before Bed | |||||
| Counteracts Morning Grogginess Instantly | |||||
| Proprietary Timed-Release Formula | |||||
| Prevents Afternoon Crash | |||||
| 0 Calories / Sugar |
Zest Wake-Up Pill
Morning Wakefulness
Zest is formulated to help you wake up alert, energized, and mentally clear — without needing to reach for coffee.
Clinical Trial Results
- In a double-blind, placebo-controlled study, participants who took the delayed-release caffeine before bed showed a 400% increase in physical readiness to move
- 71% increase in mental clarity
- 80% improvement in ease of waking — within 15 minutes of opening their eyes
- These results reflect rapid, measurable improvements across all domains of sleep inertia: physical, cognitive, behavioral, and emotional
Cognitive Performance
Zest supports faster thinking and better decision-making during the most cognitively vulnerable part of your day: right after waking.
Clinical Trial Results
- Participants had significantly faster reaction times on the psychomotor vigilance test (PVT)
- Showed improved neurobehavioral performance vs placebo — even after just 4 hours of sleep
- This marks the first time a proactive, time-synced caffeine product has shown improvements in objective cognitive metrics immediately post-wake
Mood & Emotional Well-Being
Zest promotes a positive emotional state upon waking, helping you start your day with motivation and mental resilience.
Clinical Trial Results
- On the PANAS (Positive and Negative Affect Scale), participants reported a significant boost in positive affect
- A trend toward reduced negative mood within 15 minutes of waking
- The caffeine formulation's effects were linked to dopamine activation in mood-related brain regions like the nucleus accumbens
Circadian Alignment
Zest is designed to complement your natural biological rhythms — amplifying your body’s natural cortisol spike in the morning without interfering with sleep onset.
Clinical Trial Results
- Salivary cortisol measurements showed a significant increase in cortisol levels at 60 minutes post-awakening in the caffeine group vs placebo
- Aligning with the natural cortisol awakening response (CAR)
- This suggests Zest supports healthy HPA-axis function and wake-up hormone dynamics
Sleep Integrity
Zest is engineered for nighttime use — designed to activate about 8 hours later, without disrupting your ability to fall asleep.
Additionally, since the study, we've improved the formulation and capsule technology to prevent disruption of sleep from food-induced digestive activity.
Clinical Trial Results
- Despite being taken at bedtime, the formulation showed no significant impact on sleep latency, REM sleep, or sleep efficiency in a restricted 4-hour sleep window
- The only change was a minor (~17-minute) reduction in deep sleep (N3) under specific conditions where a meal was given mid-night.
- This suggests that under normal fasting conditions, Zest preserves sleep quality
Dornbierer, D.A., Yerlikaya, F., Wespi, R. et al. A novel bedtime pulsatile-release caffeine formula ameliorates sleep inertia symptoms immediately upon awakening. Sci Rep 11, 19734 (2021). View Full Study
Science is in our core
Formulated for better days.
Validated by research.
We've partnered with leading Swiss sleep and pharmaceutical scientists to engineer a first-of-its-kind, clinically validated formula.
Years of research
In collaboration with University of Zurich and other leading research institutions, published in Nature Scientific Reports, and more
Human clinical trials
Completed human clinical trials demonstrating robustness of release profile and improvements in sleep inertia
Ongoing field studies
We are continuing to conduct studies to further demonstrate the benefits of our formulations
Patents
Proprietary capsule and delivery technologies are protected under 2 patents