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Five-star review: "I haven't woken up this good in like a decade. Wild." Justin Z, verified review. A hand holds the Zest jar against a blue sky. Five stars, 10000+ happy customers.
Zest jar with two capsules on its lid. 71% increase in cognitive clarity upon waking. 4X boost in physical readiness to move. 80% improvement in ease of waking up.
Take before bed. Wake up with instant energy. A clear capsule of micro-beads labelled with its ingredients: Vitamin B12, Zinc, Caffeine, Vitamin B5, Vitamin B6 and L-Theanine. Developed by sleep experts and Swiss neuroscientists. Clinically validated to counteract morning grogginess.

For new time zones

Zest Travel Pack

4.7 • 308 reviews
Your carry-on companion for beating jet lag and staying energized on the go. Arrive refreshed, ready to go.
$24.95

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Zest Wake-Up Pill

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Dr. Sohaib Imtiaz

Dr. Sohaib Imtiaz, MD

Zest Medical Advisor

“So many people struggle with mornings — fatigue, fog, snoozing for an hour. Zest’s delayed-release caffeine solves that in a way that aligns with how your biology actually works. As a longevity doctor, it’s one of the few sleep and energy products I genuinely recommend.”

As seen in

  • TIME
  • The New York Times
  • People
  • Nature Scientific Reports
  • Verywell Health
  • Fitt Insider
  • The San Francisco Standard
  • Wellworthy

Your recovery

Touch down on local time.

00:0006:0012:0018:0000:0006:0012:0018:001 CAPSULE2 CAPSULESOUTER RING · HOME TIMEINNER RING · LOCAL TIMEFLIGHT

  1. Before

    Get a head start

    The night before you fly, nudge your sleep toward your destination: earlier if you are flying east, later if you are flying west.

  2. During

    Fly on local time

    Set your watch to destination time when you board. Drink water, and go easy on alcohol and caffeine.

  3. Night 1

    Reset begins

    Fall asleep faster at your destination and start shifting your internal clock, even after a long flight.

  4. Night 2

    Travel fog lifts

    The brain fog fades and your circadian rhythm starts syncing to local time. Energy levels stabilize.

  5. Night 3

    Back in rhythm

    Continue nightly as needed while you settle in.

How to use

Your jet lag protocol

  1. Night before you fly

    1 capsule

    At bedtime.

  2. On the plane

    1 capsule

    About 8 hours before morning at your destination.

  3. At your destination

    2 capsules

    30–60 minutes before bed, each night you need it.

5 servings · 10 capsules in the pack

Formulation

Science-based, all natural formulation.

  • 80 mg

    Caffeine

    Enhances alertness, focus, and performance.

    Role wake

  • 80 mg

    L-Theanine

    Supports relaxed alertness, mental clarity, and smooth, sustained focus.

    Role smooth

  • 6.7 mg

    Vitamin B5

    Supports energy-yielding metabolism and reduces tiredness and fatigue.

    Role metabolism

  • 1.4 mg

    Vitamin B6

    Supports cognitive and neurotransmitter function, and reduces fatigue.

    Role metabolism

  • 80 mcg

    Vitamin B12

    Supports cellular energy production and nervous system function.

    Role metabolism

  • 3.3 mg

    Zinc

    Supports healthy cognition.

    Role support

  • 0 calories
  • 0 sugar
  • Gluten free
  • Lactose free
  • Vegan
  • Non-GMO
  • Formulated in Switzerland

Sources on our Science page

Peer-reviewedScientific Reports, 2021

A double-blind, placebo-controlled study.

In a double-blind, placebo-controlled study, participants who took the delayed-release caffeine before bed showed:

  • 400%

    increase in physical readiness to move

  • 71%

    increase in mental clarity

  • 80%

    improvement in ease of waking — within 15 minutes of opening their eyes

Read the studyOur science

Zest Medical Advisor

“So many people struggle with mornings — fatigue, fog, snoozing for an hour. Zest’s delayed-release caffeine solves that in a way that aligns with how your biology actually works. As a longevity doctor, it’s one of the few sleep and energy products I genuinely recommend.”

Dr. Sohaib ImtiazDr. Sohaib Imtiaz, MDZest Medical Advisor

Real mornings

Join 20,000+ happy customers who have transformed their mornings.

  • therealsummermason and takezest14.7k Followers

    Transcript of @therealsummermason's video: When it's time to head to bed, I reach for my Zest. Take Zest before you go to bed when energy levels are low. It dissolves while you sleep so that the caffeine is released shortly before you wake up. This means energized mornings, reduced grogginess, improved sleep-wake cycles, enhanced productivity, and steady energy. Shop Zest today.

  • shervinshares42.6k Followers

    Transcript of @shervinshares's video: The Wake Up Pill. This is Zest, from one of my good friends, actually, where you take caffeine before you go to bed, and when you wake up, the caffeine just hits you, so you’re instantly awake. This is what the Zest box looks like. You get a little bag of their supplements that goes inside of here. “Wake up with energy. Take before bed.” I’m excited to try this out, the Wake Up Pill. Time-release caffeine supplement. I think after 7 hours, the Zest caffeine will hit your blood system right as soon as you wake up. “Say hello to morning energy.” “Better for you and the planet.” There’s a refill system that comes in a pouch. “What to expect”: day one, and 3 to 7. You take Zest right before you go to bed and you wake up with energy at 6 AM. Take one capsule with water nightly. I’m excited to try Zest out. Thank you for sending us over. Follow for more.

  • drsohaibimtiaz13.8k Followers

    Transcript of @drsohaibimtiaz's video: [Upbeat rap music. No speech.] On-screen text: “Fasting and morning caffeine withdrawal headaches?” “Tired in the morning but don’t want coffee?” “Zest: delayed-release caffeine pill taken at night.”

  • maria.georgas536.8k Followers
    Instagram story by @maria.georgas
  • oliviaalboher263.8k Followers

    Transcript of @oliviaalboher's video: Zest. These are life-changing. Life-changing. We just started taking them. We take one every single night, 30 minutes before we go to bed, and we wake up energized than ever, literally feeling like the Energizer Bunny. Don’t even need a coffee.

  • itsethankeiser310.8k Followers

    Transcript of @itsethankeiser's video: Does anyone else spend hours on social media when they wake up? Because I wake up and I first go to Instagram, then I go to TikTok. Then I check the stock market, then I go to crypto, and then I repeat the cycle. It’s like a fucking loop. And I do this over and over again. And I wanted to find a way to break this cycle. I found this product. It’s called Zest. It’s like a caffeine pill on an 8-hour timer. So I take it before I go to bed, and then when I wake up, the caffeine hits me or it wakes me up, and it forces me out of bed because I have all this energy. I literally cannot stay in bed. So this is a solution that’s been working for me. It’s called takezest.com. Um, pretty interesting stuff. So if you want to try it for yourself, if you have a hard time getting out of bed, try it for yourself. Put a link here and let me know what you think.

  • maguireamundsen209.2k Followers
    Instagram story by @maguireamundsen

    “probably the only thing that got me through my exhaustion today”

  • jakeheyen and wellworthymedia130.5k Followers
  • prettywithlee115.3k Followers
    Instagram story by @prettywithlee

    “Took one before bed and woke up feeling so energized”

  • ross.poweredbyplants1.3k Followers

    Transcript of @ross.poweredbyplants's video: On-screen text: “Struggle to get up in the morning? @takezest has been a game changer for me. 8 hour delayed release caffeine & L-Theanine.”

Reviews · Wake-Up Pill

What Wake-Up Pill customers say

FAQ

Frequently asked questions

On the trip

Who is the Travel Pack for?

The Travel Pack is designed for anyone who crosses time zones and wants to minimize jet lag. Whether you travel for work, vacation, or athletics, this product helps you adjust to new time zones faster.

When should I take it?

Take 1 capsule at bedtime the night before you fly, and 1 on the plane, about 8 hours before morning at your destination. At your destination, take 2 capsules 30–60 minutes before bedtime, each night you need it.

Can I use it when returning home?

Yes. The Travel Pack works for both outbound and return travel. Follow the same protocol.

Is it safe for frequent travelers?

Designed for repeat use on every trip. Check with your doctor if you have questions about regular use.

How is this different from melatonin?

Unlike standalone melatonin supplements, the Travel Pack combines Zest's proprietary timed-release caffeine technology with ingredients that support circadian rhythm adjustment. It doesn't just help you fall asleep — it helps you wake up energized and aligned with local time.

Can I take it with other supplements or medications?

We recommend consulting your physician if you are taking prescription medications. Avoid combining with other sleep aids or caffeine-containing products within the same time window.

What should I avoid while using it?

Avoid alcohol and other sleep medications while using the Travel Pack for best results. Stay hydrated during travel.

Does it contain caffeine?

Yes. The Travel Pack contains Zest's proprietary delayed-release caffeine, designed to release at the optimal time to support your wake-up and circadian adjustment.

About the Wake-Up Pill

Does this replace my morning coffee?
Zest is formulated to contain about the same amount of caffeine as a cup of coffee. We are coffee lovers ourselves, and designed it so that it can be both a supplement or a replacement to coffee. If you find yourself wanting a cup of coffee in the morning or afternoon, you can do so without any issues.
What are the advantages of using Zest's delayed-release caffeine capsule over taking a regular caffeine pill in the morning?
When you consume caffeine, the caffeine embarks on a 15 to 20-minute journey through your small intestine, into your bloodstream. This typically means it make take half an hour or more, to feel the effects of a caffeine pill, or a cup of coffee - which is more time you'll have to spend suffering through symptoms of "sleep inertia" - the morning grogginess you typically feel in the morning when you first wake up. Zest's proprietary delayed-release capsule gradually releases caffeine and other active ingredients, after an initial 7 hour delay. This allows you to wake up with caffeine already in your bloodstream, counteracting sleep inertia and helping you feel alert and energized from the moment you wake up.
Why is caffeine more effective while asleep?
While you're awake and going about your day, a chemical compound called adenosine gradually accumulates in parts of your brain. Adenosine is typically what makes you feel drowsy and ready for bed. Caffeine works by binding to adenosine receptors in our brain. When caffeine binds to those receptors, it blocks our ability to feel the effects of adenosine, so we feel less sleepy, more energetic and focused. Because adenosine is cleared from your brain when you sleep, this frees up the receptors such that caffeine is able to more effectively bind to them. This effectively means that you'll be able to better feel the effects of caffeine, and feel more alert and focused as a result.
Does using a timed-release caffeine capsule restrict the amount of time I can sleep?
For the average person, the recommended amount of sleep time is around 7-9 hours. We've carefully designed our pill to best suit everyone's sleep needs, such that you'll only wake up after 7-8 hours. We recommend consistently taking the capsule for a few weeks, which will help your body naturally regulate a consistent sleep schedule and wake-up time.
How does caffeine affect my sleep cycles?
Typically, when you wake up during the later part of a sleep cycle, you may experience grogginess, as you are in REM sleep, or deep sleep, also known as NREM stage 3 and stage 4. This is often why short 20 minute naps are recommended over longer naps, unless you can sleep for a full 90-minute sleep cycle. We've designed our capsule to release caffeine towards the end of your sleep cycle, and timed it such that you're less likely to be in these stages when the caffeine activates. Additionally, once released, caffeine helps ensure that you wake up naturally from a lighter sleep stage and thus, mitigating the effects of sleep inertia from waking up suddenly from a deeper sleep stage.
What if I want to sleep for more than 8 hours?
If you need more than 8 hours of sleep, you can always opt to not take the timed-release capsule. Additionally, if your body is sleep-deprived, your accumulated sleep debt, and your corresponding "sleep drive" or "sleep pressure" may outweigh the caffeine's effects. This means you may not wake up from the caffeine.
How is Zest different from other timed-release caffeine products?
Our product stands out in several key ways: 1. Advanced Release Mechanism: Our delayed-release coating is highly advanced, developed in collaboration with pharmaceutical scientists and neuroscientists. Unlike other products, which may release caffeine prematurely, our formulation is designed to reliably release caffeine after 7–8 hours of sleep, ensuring you wake up feeling refreshed and alert. This has been clinically validated — read our published peer-reviewed study here. 2. True Delayed-Release, Not Just Extended/Sustained-Release: Many products labeled as "extended-release" or "sustained-release" gradually release caffeine over time, starting shortly after ingestion. In contrast, Zest is a true delayed-release system that holds off releasing caffeine for a full 7 hours, perfectly timed to coincide with waking up, sustained over the course of 2+ hours. This ensures the caffeine works exactly when you need it, without interfering with your sleep, and without causing a crash. 3. Scientifically Backed and Validated: We've invested heavily in the development and testing of our release technology to ensure robustness and reliability. Our formula has been rigorously tested to provide consistent results, so you don't wake up too early or experience uneven effects. 4. Premium Ingredients: We source the highest quality ingredients from trusted European suppliers in countries like Switzerland and Germany. This ensures both effectiveness and safety for our users. While our product is priced higher than some alternatives, we believe it delivers unparalleled quality and performance. If you're looking for a reliable, science-backed solution, we believe Zest to be the best option available. Learn more about our science and our background here.
What if I have insomnia?
This product is not intended to treat, cure, or prevent clinical sleep disorders. The following section is for educational and information purposes only, does not constitute providing medical advice. Always consult your physician or clinician before using this product. The gold standard treatment for insomnia is CBT-i. The first line of treatment technique in CBT-i is often "sleep restriction therapy", which involves restricting the amount of time you spend in bed. Zest can help support waking up at a set time every day, and help you better anchor your wake-up times to be more consistent. In this particular case, taking a caffeine-based product such as Zest can be beneficial for managing symptoms of insomnia and aligning your circadian rhythms.
I've heard I'm not supposed to consume caffeine until 90 minutes after waking up?
Don't worry - this recently trending advice from Dr. Huberman is not strongly supported by science. One of the biggest claims behind delaying caffeine is that it prevents interfering with the body's natural cortisol rhythm. But this argument is misleading. The idea that delaying caffeine prevents "extending" the cortisol peak is also flawed. Caffeine will still cause a rise in cortisol even if you delay intake, meaning the timing doesn't make much difference compared to the amount. If avoiding cortisol spikes were truly a concern, then morning workouts should also be discouraged—yet research overwhelmingly supports early exercise for energy and metabolism. To mitigate an afternoon crash, our timed-release capsule gradually releases caffeine, and maintains a more gradual and consistent level of caffeine in your bloodstream, avoiding any large spikes and subsequent crashes. This steady release helps sustain your energy levels throughout the day and avoid any afternoon crashes from caffeine. Read more here.
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Your best mornings start the night before.

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